Threema allows you to verify that the ID of the person you are communicating with is really theirs by scanning their QR code.
If you are sure about your chat partner’s ID, then there’s no way for an attacker to spoof or intercept/decrypt a message from or to your chat partner.
The connection between the app and the servers is secure against MITM attacks because the server authenticates itself to the app based on a public key that is hard-coded into the app and whose corresponding secret key is only known by the legitimate servers.
Please note: Threema can only be as secure as the device that it is running on. Malware that runs in the background on your device can intercept and falsify data without being noticed. We highly recommend to always install the most recent operating system updates and to only use software from trusted sources.